Julie Kaiser’s most recent work describes the role of branched-chain amino acids in bacterial adaptation to nutrient starvation. The paper is entitled “Branching Out: Alterations in Bacterial Physiology and Virulence Due to Branched-Chain Amino Acid Deprivation”.
Ron Flannagan's most recent work on the interaction of S. aureus with macrophages was published in mBio. Thanks to contributions from Robert Kuiack in Martin McGavin's lab on the study. The paper is entitled "Staphylococcus aureus uses the GraXRS regulatory system to sense and adapt to the acidified phagolysosome in macrophages"
Ron Flannagan and David Watson worked closely together on a study that investigated the survival of S. lugdunensis in macrophages. Thanks to Bas Surewaard from the Kubes lab in Calgary for a great collaboration! The paper, entitled "The surreptitious survival of the emerging pathogen Staphylococcus lugdunensis within macrophages as an immune evasion strategy" is published in Cellular Microbiology
In collaboration with the Brinsmade Lab at Georgetown University, the Murphy Lab at the University of British Columbia, and the Edgell Lab at Western University, our paper describes the mechanisms regulating branched-chain amino acid synthesis in Staphylococcus aureus. The study describes the nutritional cues that regulate whether S. aureus acquires BCAAs or synthesizes them itself.